Contributions to nephrology vol. 144: Sepsis, kidney and multiple organ dysfunction
نویسندگان
چکیده
منابع مشابه
Epidemiology of sepsis and multiple organ dysfunction syndrome in children.
STUDY OBJECTIVES To determine the cumulated incidence and the density of incidence of systemic inflammatory response syndrome (SIRS), sepsis, severe sepsis, septic shock, and multiple organ dysfunction syndrome (MODS) in critically ill children; to distinguish patients with primary from those with secondary MODS. DESIGN Prospective cohort study. SETTING Pediatric ICU of a university hospita...
متن کاملThe evolution and therapy aspects in multiple organ dysfunction sepsis
Background Severe sepsis was the subject of intense debate over the years, and in the last twenty years there has been a constant effort to identify therapies that reduce mortality. Although the inflammatory response is often adapted to the etiologic agent and to the increase of the mediators in association with organ dysfunction, it is not currently possible to rapidly assess the patients’ abi...
متن کاملEffects of Continuous Erythropoietin Receptor Activator in Sepsis-Induced Acute Kidney Injury and Multi-Organ Dysfunction
BACKGROUND Despite advances in supportive care, sepsis-related mortality remains high, especially in patients with acute kidney injury (AKI). Erythropoietin can protect organs against ischemia and sepsis. This effect has been linked to activation of intracellular survival pathways, although the mechanism remains unclear. Continuous erythropoietin receptor activator (CERA) is an erythropoietin w...
متن کاملThe Relationship between Plasma Levels of Interleukin-6, Multiple Organ Dysfunction and Mortality in Orthopedic Patients
Background: Interleukin 6 (IL-6) functions as both a pro-inflammatory cytokine and an anti-inflammatory cytokine. Objective: To evaluate the levels of IL-6 in patients with multiple organ dysfunction syndrome (MODS). Methods: Level of IL-6 was assessed and recorded for 14 days subsequent to the injury in 161 multiple trauma patients. MODS were diagnosed using Marshal Score. Injury Severity Scor...
متن کاملThe role of the endothelium in severe sepsis and multiple organ dysfunction syndrome.
Severe sepsis, defined as sepsis with acute organ dysfunction, is associated with high morbidity and mortality rates. The development of novel therapies for sepsis is critically dependent on an understanding of the basic mechanisms of the disease. The pathophysiology of severe sepsis involves a highly complex, integrated response that includes the activation of a number of cell types, inflammat...
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ژورنال
عنوان ژورنال: Canadian Journal of Anesthesia/Journal canadien d'anesthésie
سال: 2005
ISSN: 0832-610X,1496-8975
DOI: 10.1007/bf03018602